At the heart of the federal requirements
is the Public Health Service Policy on Humane Care and
Use of Laboratory Animals in testing, research and training.
This policy provides the basis of the operational guidelines
for the Miami University IACUC.
In addition, the Universitys
policies on animal use adhere to the federal requirements
of the Animal Welfare Act (7 U.S.C. 2131 et seq.), the
United States Department of Agricultures (USDA)
Guide for the Care and Use of Agricultural Animals,
and the National Research Councils Guide for the
Care and Use of Laboratory Animals.
The USDA and the National Institutes
of Healths Office for Laboratory Animal Welfare
(OLAW) administer the federal regulations. The USDA
Animal and Plant Health Inspection Service enforces
the Animal Welfare Act primarily by inspecting animal
care and use facilities. OLAW administers and coordinates
the Public Health Service Policy primarily by requiring
institutions to adhere to assurance documents.
Miami Universitys assurance identifies the Universitys
responsibilities and explains what the University does
to meet the federal regulations for animal care and
use. The IACUC ensures that the assurance is upheld.
University Policies on Animal Use
To ensure the availability of
quarantine and animal housing space, please contact
Linda R. Zehler,
Director, Miami University Laboratory Animal Resources,
before placing an order for research animals.
Beverages, or Smoking in Animal Rooms is not permitted.
Investigators are not permitted
to smoke or take food or drinks into the animal facilities.
of Lab Animals
All research animals should have
a permanent form of identification. Acceptable ID is
cage cards, tattooing, indelible marker, ear or toe
punching, collars or tags. Cage cards should contain
the investigators name, vendor name, strain of animal,
date of birth or weight, sex of the animal, and approved
protocol number. Permanent identification, in addition
to a cage card is desirable when data on individual
animals is critical.
Quarantine time on incoming animals
is 7 days. During the quarantine period animals will
be held in a designated quarantine room to be observed
for signs of illness. All incoming animals should be
allowed to stabilize for at least 48 hours after their
arrival. If quarantined animals show no signs of disease
or injury after the initial stabilization period they
may begin experimental procedures during their quarantine
period. Quarantined animals may be taken to labs or
classrooms provided other research animals do not come
into contact with them. It is possible that an animal
order would be delayed because quarantine space is not
available. Please contact the Supervisor of Animal Care
before ordering animals.
A variety of vendors supply lab
animals to the University. Animals from different vendors
generally are not maintained in the same animal room
to prevent the possible spread of disease. Animal orders
will be checked to ensure the compatibility of the order
with existing colonies in the facility.
in Animal Rooms
Federal regulations require that
equipment found in animal rooms have smooth impervious
surfaces that will not attract or retain dirt. Wood,
galvanized metal, or other services which will corrode
are not appropriate for animal rooms since they cannot
be properly sanitized. If equipment such as balances
or microscopes must be kept in animals rooms it should
be placed on a stainless steel cart so that animal aides
can easily move it to clean floors and walls.
Performed in Animal Rooms
Animals should be housed in an
environment which minimizes stress and exposure to agents
which might add to experimental variables. Procedures
which cause pain or distress to a research animal will
disturb the entire room of animals, and therefore, should
be conducted in an area other than the animal rooms.
Any work done with volatile agents should be performed
under appropriate hoods rather than in the animal room.
and Pest Control
Animal facility personnel try
to control insects and pests with proper sanitation
and waste control. Please do not bring cardboard boxes,
equipment, or waste which might harbor insects or vermin
into the animal facilities. This is particularly important
in items used for field work
Products Used for Animal Feed
Grain products harbor a variety
of insects which can contaminate animal feeds. Any grain
products which are used or stored in the animal facility
should be routinely decontaminated. No grain product
should be taken into the animal rooms without first
checking with the Animal Facility Supervisor for decontamination
The USDA regulates the housing
and care of all wild mammals. These animals must be
kept in accordance with federal regulations and are
subject to inspection on a routine basis. Because of
the risk of infection to laboratory animals, wild species
cannot be housed in the Pearson Hall Animal Facility.
Provisions should be made to maintain these animals
at the ERC, in environmental chambers or other isolated
areas. Please notify the Supervisor of Animal Facilities
of your intent to house wild species so that appropriate
housing can be found.
Request for animal facility staff
time to assist with research projects should be made
through Linda Zehler,
Director, Miami University Laboratory Animal Resources.
The University Animal Facilities
must comply with federal regulations and maintain uniformity
in its animal caging. If an investigator needs caging
or wishes to purchase caging with research funds please
check with the Animal Facilities Supervisor before doing
so. This will insure that the caging is needed, will
meet current federal guidelines, and is consistent with
the existing inventory. All caging in Miami University
Animal Facilities shall be considered part of a departmental
cage inventory and will be maintained and stored accordingly.
Caging obtained from grants or other funds from individual
investigators will be maintained as regular inventory,
according to the specific cleaning protocols for each
Involving Animal research
The University has limited animal
housing space available. With the large number of grants
being submitted to funding agencies, it is difficult
to predict the numbers of animals or species that will
require housing from year to year. It is possible that
space or appropriate caging may not be immediately available
when projects are funded. Every effort will be made
to anticipate and minimize delays.